Profile

Bowers, K. and T.H. Stevens. Protein transport from the late Golgi to the vacuole in the yeast Saccharomyces cerevisiae. Biochim. Biophys. Acta, 1744, 438-454 (2005).

Malkus, P., Graham, L.A., Stevens, T.H. and R. Schekman. Role of Vma21p in assembly and transport of the yeast vacuolar ATPase. Mol. Biol. Cell, 15, 5075-5091 (2004).

Flannery, A.R., Graham, L.A. and T.H. Stevens. Topological characterization of the c, c', and c'' subunits of the Vacuolar ATPase from the yeast Saccharomyces cerevisiae. J. Biol. Chem., 279, 39856-39862 (2004).

Bowers, K., Lottridge, J., Helliwell, S.B., Goldthwaite, L.M., Luzio, J.P. and T.H. Stevens. Protein-protein interactions of ESCRT complexes in the yeast Saccharomyces cerevisiae. Traffic, 5, 194-210 (2004).

Graham, L.A., Bowers, K., Flannery, A.R. and T.H. Stevens. The role of the V-ATPase in the cellular physiology of the yeast Saccharomyces Cerevisiae. Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology, Futai, Kaplan & Wada eds., 355-377 (2004).

Bowman, E.J., Graham, L.A., Stevens, T.H. and B.J. Bowman. The bafilomycin/concanamycin binding site in subunit c of the V-ATPases from Neurospora crassa and Saccharomyces cerevisiae. J. Biol. Chem., 279, 33131-33138 (2004).

Graham, L.A., Flannery, A.R. and T.H. Stevens. Structure and assembly of the yeast V-ATPase. J. Bioenerg. Biomembr., 35, 301-312 (2003).

Conibear, E., Cleck, J.N. and T.H. Stevens. Vps51p mediates the association of the GARP (Vps52/53/54) complex with the Golgi t-SNARE Tlg1p. Mol. Biol. Cell, 14, 1610-1623 (2003).

Kweon, Y., Rothe, A., Conibear, E. and T.H. Stevens. Ykt6p is a multifunctional yeast R-SNARE that is required for multiple membrane transport pathways to the vacuole. Mol. Biol. Cell, 14, 1868-1881 (2003).

Conibear, E. and T.H. Stevens. Studying yeast vacuoles. Methods Enzymol., 351, 408-432 (2002).

Kawasaki-Nishi, S., Bowers, K., Nishi, T., Forgac, M. and T.H. Stevens. The amino-terminal domain of the V-ATPase a subunit controls targeting and in vivo dissociation and the carboxyl-terminal domain affects coupling of proton transport and ATP hydrolysis. J. Biol. Chem., 276, 47411-47120 (2001).

Sagermann, M., Stevens, T.H. and B.W. Matthews. Crystal structure of the regulatory subunit H of the V-type ATPase of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA, 98, 7134-7139 (2001).

Bowers, K., Levi, B.P., Patel, F.I. and T.H. Stevens. The sodium/proton exchanger Nhx1p is required for endosomal protein trafficking in the yeast Saccharomyces cerevisiae. Mol. Biol. Cell, 11, 4277-4294 (2000).

Powell, B., Graham, L.A. and T.H. Stevens. Molecular characterization of the yeast vacuolar H+-ATPase proton pore. J. Biol. Chem., 275, 23654-23660 (2000).

Gerrard, S.R., Levi, B.P. and T.H. Stevens. Pep12p is a multifunctional yeast syntaxin that controls entry of biosynthetic endocytic and retrograde traffic into the prevacuolar compartment. Traffic, 1, 259-269 (2000).

Gerrard, S.R., Bryant, N.J. and T.H. Stevens. Vps21 controls entry of endocytosed and biosynthetic proteins into the yeast prevacuolar compartment. Mol. Biol. Cell, 11, 613-626 (2000).

Conibear E. and T.H. Stevens. Vps52p, Vps53p and Vps54p forms a novel multisubunit complex required for protein sorting at the yeast late Golgi. Mol. Biol. Cell 11, 305-323 (2000).

Graham, L.A., Powell, B. and T.H. Stevens. Composition and assembly of the yeast vacuolar H+-ATPase complex. J. Exp. Biol. 203, 61-70 (2000).

Gerrard, S.R., Mecklem, A.B. and T.H. Stevens. The yeast endosomal t-SNARE, Pep12p, functions in the absence of its transmembrane domain. Traffic 1, 45-55 (2000).

Tishgarten, T., Yin, F.F., Faucher, K., Dluhy, R., Fischer von Mollard, G., Stevens, T.H. and L.A. Lipscomb.  Novel structures and oligomerization states for yeast v- and t-SNAREs.  Prot. Sci. 8, 2465-2473 (1999).

Ungermann, C., Fischer von Mollard, G., Jensen, O.N., Margolis, N., Stevens, T.H. and W. Wickner.  Three v-SNAREs and two t-SNAREs are essential for homotypic vacuole fusion.  J. Cell Biol. 145, 1435-1442 (1999).

Zheng, H., Fischer von Mollard, G., Kovaleva, V., Stevens, T.H. and N.V. Raikhel.  The Plant v-SNARE AtVTI1a Likely Mediates Vesicle Transport from the TGN to the Prevacuole.  Mol. Biol. Cell 10, 2251-2264 (1999)

Fischer von Mollard, G. and T.H. Stevens.  TheSaccharomyces cerevisiae: v-SNARE Vti1p is required for multiple transport pathways to the vacuole.  Mol. Biol. Cell 10, 1719-1732 (1999).

Graham, L.A. and T.H. Stevens.  Assembly of the yeast vacuolar proton-translocating ATPase.  J. Bioener. and Biomem. 31, 39-47 (1999).

Conibear, E. and T.H. Stevens (1998) Multiple sorting pathways between the late Golgi and the vacuole in yeast. Biochim. Biophys. Acta 1404: 211-230.

Bryant, N.J., Piper, R.C., Weisman, L.S. and T.H. Stevens (1998) Retrograde traffic out of the yeast vacuole to the TGN occurs via the prevacuolar/endosomal compartment. J. Cell Biol. 142: 651-663.

Graham, L.A., Hill, K.J. and T.H. Stevens (1998) Assembly of the yeast vacuolar H+-ATPase occurs in the endoplasmic reticulum and requires a Vma12p/Vma22p assembly complex. J. Cell Biol. 142: 39-49.

Bryant, N.J., Piper, R.C., Gerrard, S.R. and T.H. Stevens (1998) Traffic into the prevacuolar/endosomal compartment of Saccharomyces cerevisiae: a VPS45-dependent intracellular route and a VPS45-independent, endocytic route. Eur. J. Cell Biol. 76: 43-52.

Fischer von Mollard, G. and T.H. Stevens (1998) A human homologue can functionally replace the yeast v-SNARE Vti1p in two vesicle transport pathways. J. Biol. Chem. 273: 2624-2630.

Voos, W. and T.H. Stevens (1998) Retrieval of resident late-Golgi membrane proteins from the prevacuolar compartment of Saccharomyces cerevisiae is dependent on the function of Grd19p. J. Cell Biol. 140: 577-590.

Bryant, N.J. and T.H. Stevens (1998) Vacuole biogenesis in Saccharomyces cerevisiae: protein transport pathways to the yeast vacuole. Microbiol. and Molec. Biol. Rev. 230-247.

Jackson, D.D. and T.H. Stevens (1997) VMA12 encodes a yeast endoplasmic reticulum protein required for vacuolar H+-ATPase assembly. J. Biol. Chem. 272: 25928-25934.

Tomashek, J.J., Graham, L.A., Hutchins, M.U., Stevens, T.H. and D.J. Klionsky (1997) V1-situated stalk subunits of the yeast vacuolar proton-translocating ATPase. J. Biol. Chem. 272: 26787-26793.

Stevens, T.H. and M. Forgac (1997) Structure, function and regulation of the vacuolar H+-ATPases. Ann. Rev. Cell & Devel. Biol. 13: 779-808.

Piper, R.C., Bryant, N.J. and T.H. Stevens (1997) The membrane protein alkaline phosphatase is delivered to the vacuole by a route that is distinct from the VPS-dependent pathway. J. Cell Biol. 138: 531-545.

Fischer von Mollard, G., Nothwehr, S.F. and T.H. Stevens (1997) The yeast v-SNARE mediates two vesicle transport pathways through interactions with the t-SNAREs Sed5p and Pep12p. J. Cell Biol. 137: 1511-1524.

Tellam, J.T., James, D.E., Stevens, T.H. and R.C. Piper (1997) Identification of a mammalian Golgi Sec1p-like protein; mVps45p. J. Biol. Chem. 272: 6187-6193.

Bryant, N.J. and T.H. Stevens (1997) Two separate signals act independently to localize a yeast late-Golgi membrane protein through a combination of retrieval and static retention. J. Cell Biol. 136: 287-297.

Hirata, R., Graham, L.A., Takatsuki, A., Stevens, T.H. and Y. Anraku (1997) VMA11 and VMA16 encode the second and third proteolipid subunits of the Saccharomyces cerevisiae vacuolar membrane H+-ATPase. J. Biol. Chem. 272: 4795-4803.

Cooper, A.A. and T.H. Stevens (1996) Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases. J. Cell Biol. 133: 529-541.

Nothwehr, S.N., Bryant, N.J. and T.H. Stevens (1996) The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins. Mol. Cell. Biol. 16: 2700-2707.

Chen, Y.-J. and T.H. Stevens (1996) The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae. Eur. J. Cell Biol. 70: 289-297.

Ekena, K. and T.H. Stevens (1995) The Saccharomyces cerevisiae MVP1 gene interacts with VPS1 and is required for vacuolar protein sorting. Mol. Cell. Biol. 15: 1671-1678.

Nothwehr, S.F., Conibear, E. and T.H. Stevens (1995) Golgi and vacuolar membrane proteins reach the vacuole in vps1 mutant yeast cells via the plasma membrane. J. Cell Biol. 129: 35-46.

Hill, K.J. and T.H. Stevens (1995) Vma22p is a novel endoplasmic reticulum-associated protein required for assembly of the yeast vacuolar H+-ATPase Complex. J. Biol. Chem. 270: 22329-22336.

Piper, R.C., Cooper, A.A., Yang, H. and T.H. Stevens (1995) Vps27p controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae. J. Cell Biol. 131: 603-617.

Hill, K. J., and T. H. Stevens (1994) Vma21p is a yeast membrane protein retained in the endoplasmic reticulum by a di-lysine motif and is required for the assembly of the vacuolar H+-ATPase Complex. Mol. Biol. Cell 5: 1039-1050.

Piper, R. C., E. A. Whitters, and T. H. Stevens (1994) Yeast Vps45p is a Sec1p-like protein required for the consumption of vacuole-targeted, post-Golgi transport vesicles. Eur. J. Cell Biol. 65: 305-318.