Profile

Pigg, H.C., Yglesias, M.V., Sutton, E.C., McDevitt, C.E., Shaw, *M., DeRose, V.J. Time-dependent studies of oxaliplatin and other nucleolar stress-inducting platinum compounds. ACS Chem. Biol. 2022, 17, 2262-2271. DOI: 10.1021/acschembio.2c00399.https://pubs.acs.org/doi/full/10.1021/acschembio.2c00399

^*McDevitt, C.E., ^*Guerrero, A.S., Smith, H.M., DeRose V.J. Influence of ring modifications on nucleolar stress caused by oxaliplatin-like compounds. ChemBioChem, 2022, e20220013, (Very Important Paper designation); DOI:10.1002/cbic.202200130. https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cbic.202200130

Hunsicker-Wang, L.M., Vogt, M.J., Hoogstraten, C.F., Cosper, N.J., Davenport, A.M., Hendon, C.H., Scott, R.A., Britt, R.D., DeRose, V.J. Spectroscopic characterization of Mn²⁺ and Cd²⁺ coordination to phosphorothioates in the conserved A9 metal site of the hammerhead ribozyme. J. Inorg. Biochem. (Special issue in honor of Richard Holm) 2022, 230, 111754-111767. DOI 10.1016/j.jinorgbio.2022.111754

Sutton, E.C. and DeRose, V.J. Early nucleolar responses differentiate mechanisms of cell death induced by oxaliplatin and cisplatin. J. Biol. Chem. 296, 2021.  DOI 10.1016/j.jbc.2021.100633. https://www.sciencedirect.com/science/article/pii/S0021925821004191?via%3Dihub

Yglesias, M.V. and DeRose, V.J. ‘Metal ion interactions with DNA, RNA, and ribozymes’ Chapter in Comprehensive Coordination Chemistry III Vol. 8, Y. Lu, L. Que, Eds., Elsevier, Oxford, 2021, pp. 968-993. DOI 10.1016/B978-0-08-102688-5.00112-4

DeRose, V.J. and Michel, S. Editorial overview: Bioinorganic chemistry: Metals in biology: approaching the big picture. Current Opinion in Chemical Biology 2020, 55, A4–A6.  DOI 10.1016/j.cbpa.2020.03.002

 

Nucleolar Stress Induction by Oxaliplatin and Derivatives

Emily Sutton*, Christine McDevitt*, Jack Prochnau, Matthew Yglesias, Austin Mroz, Min Chieh Yang, Rachael Cunningham, Christopher Hendon, Victoria J. DeRose,  J. Am. Chem. Soc. 2019 141(46), 18411-18415 Link

 

Monofunctional platinum(II) compounds and nucleolar stress: Is phenanthriplatin unique?

Christine McDevitt, Matthew Yglesias, Austin Mroz, Emily Sutton, Min Chieh Yang, Christopher Hendon, Victoria J. DeRose,  J Biol Inorg Chem. 2019 24(6), 899-906 Link

 

Mapping platinum adducts on yeast ribosomal RNA using high- throughput sequencing

Kory Plakos and Victoria J. DeRose Chem Comm, 2017 53(95), 12746-12749 Link

 

Platinum Binds Proteins in the Endoplasmic Reticulum of S. cerevisiae and Induces Endoplasmic Reticulum Stress

Rachael M. Cunningham and Victoria J. DeRose ACS Chem. Biol., 2017 12(11), 2737-2745 Link

 

Beyond Mg(2+) : functional interactions between RNA and transition metals

Adam M. Saunders and Victoria J. DeRose Curr Opin Chem Biol, 2016 31, 153-159 Link

 

Multifunctional Pt(II) Reagents: Covalent Modifications of Pt Complexes Enable Diverse Structural Variation and In-Cell Detection

Jonathan D. White, Michael M. Haley, and Victoria J. DeRose Acc. Chem. Res., 2016 49(1), 56-66Link

 

Nucleic Acid Catalysis: Metals, Nucleobases, and Other Cofactors

W. Luke Ward, Kory Plakos, and Victoria J. DeRose Chem. Rev. 2013, 135 (32), pp 11680–11683 Link